Fig. 6
From: Leucinostatins from fungal extracts block malaria transmission to mosquitoes
Structures of the four active compounds were determined as different derivatives of leucinostatins. The compound of C1, leucinostatin B, contains the substituent –CH3 in position R1, R2=CH3CH2COCH2(OH)CH-, R3 = –H and R4 = –CH3 while the compound of C3, leucinostatin B2, only has the different substituent –CH3CH2COCH=CH– in position R2. Another difference exists at position R3, which is observed with the substituents -CH3 in the compound of C2 and C4 (leucinostatins A and A2) compared with C1 and C3, respectively