Table 1 Contact-wise TB activity of antimalaria compound sprays (100 μM/m2)
From: Leucinostatins from fungal extracts block malaria transmission to mosquitoes
Compounds | Reduction in oocyst number/midgut (%) | TB activity (%) | P-value to the negative control |
|---|---|---|---|
Leucinostatin A | 98.7 | 94.8 | < 0.0001 |
Quinine | 12.5 | 0 | 0.83 |
Primaquine | 23.3 | 41.2 | 0.015 |
Artemisinin | 15.8 | 9.2 | 0.47 |
Artemether | 3.2 | 0 | 0.89 |
Arteether | 31.3 | 18.9 | 0.16 |
Artesunate | 33.3 | 19.8 | 0.32 |
Pyrimethamine | 0 | 8.1 | 0.95 |
Sulfadoxine | 2.2 | 0 | 0.92 |
Methylene blue | 71.7 | 48.4 | 0.0002 |
Asperaculane B | 10.9 | 2.7 | 0.73 |
Salinomycin | 18.2 | 0 | 0.62 |
Atovaquone | 99.3 | 96.8 | < 0.0001 |