Fig. 1
Combined treatment with TAU and ART effectively prolonged the survival time of mice infected with Plasmodium berghei ANKA strain and reduced parasitaemia. A, B Wild-type (WT) C57BL/6 mice were intraperitoneally infected with P. berghei ANKA strain (1 × 105 infected red blood cells). The survival time of the mice in the ART + TAU group was significantly prolonged (A) and parasitaemia was significantly reduced (B) compared to that in the ART only and TAU only groups. n = 10 mice per group. The data represent the mean ± standard error of the mean. P values were calculated by the log-rank (Mantel‒Cox) test (A) and by the area under the curve (B). ART, Artemisinin; ART + TAU, ART and TAU co-therapy; TAU, taurine