Fig. 4

ROC analysis of potential biomarkers and determination of the predictive power of differentially abundant metabolites. a 2-Methylbutyrylglycine, b 3,3-dimethylglutaric acid, c 1,7-dihydroxyxanthone, d trimethylamine N-oxide, e 9-hydroperoxy-10E,12Z,15Z-octadecatrienoic acid, f 5,12-dihydroxy-6,8,10,14,17-eicosapentaenoic acid. AUC values closer to 1 indicate improved diagnostic effectiveness, while an AUC of 0.5 signifies complete ineffectiveness and lack of diagnostic value