Fig. 4
From: Glabridin exhibits potent inhibitory effects against Toxoplasma gondii in vitro and in vivo
Glabridin-induced transcriptomic changes in Toxoplasma gondii. a Heatmap of Pearson correlation coefficients between samples. b Unsupervised hierarchical clustering of RNA sequencing (RNA-seq) data, with normalized FPKM values (green: low expression, red: high expression). Columns are hierarchically clustered using Pearson correlation as the distance metric. c Volcano plot displaying − log10 (Q values) versus RNA expression ratio between the glabridin-treated group and control (0.1% DMSO). d Gene Ontology (GO) analysis of differentially expressed genes (DEGs), with the X-axis indicating -log10(P value) and the Y-axis showing GO terms. e Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis of DEGs, where the X-axis represents the enrichment ratio and the Y-axis lists KEGG pathway terms. Dot color indicates P value, and dot size reflects the number of DEGs enriched in each KEGG pathway