Fig. 6

SARM inhibited ERK phosphorylation. A, HT22 cells were transiently transfected with 4 μg of SARM plasmids after 24 h of overexpression of SARM and co-cultured with T. gondii tachyzoites for 24 h, and ERK phosphorylation was detected via western blot. B, HT22 cells were stably transfected with SARM and co-cultured with T. gondii tachyzoites for 24 h, and ERK phosphorylation was detected via western blot. C, BV2 cells were transiently transfected with 4 μg of SARM plasmids after 24 h of overexpression of SARM and co-cultured with T. gondii tachyzoites for 24 h; ERK phosphorylation was detected via western blot. n = 3 per group. Data are shown as mean ± SD. ns, not significant; *P < 0.05; ***P < 0.001