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Fig. 8 | Parasites & Vectors

Fig. 8

From: Advances in the study of extracellular vesicles of Naegleria fowleri and their role in contact-independent pathogenic mechanisms

Fig. 8

Naegleria fowleri EVs induce necrosis but not apoptosis in MDCK cells. Apoptosis and necrosis were assessed through Annexin V (green) and propidium iodide (red) staining, respectively. A Control culture: no evidence of apoptosis or necrosis was observed. B MDCK cells underwent necrosis following interaction with EVs. C EVs induced necrosis in MDCK cells, even when they were incubated with PMSF. D Percentage of necrotic cells in cultures (*P < 0.05); n = 3. Bar = 20 µm

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